FST 344 1mg

Identity & specification

Amount in vial

Contents

fst-344-1mg

Purity

>99%

SKU

fst-344-1mg

5 or more 5%
10 or more 10%
50 or more 20%
100 or more 25%

€87.78

Purity

≥99%

Storage

Refrigerate 2–8°C

COA

With every order

Use

Research only

For research use only. Not for human or veterinary use, diagnostic procedures, or food applications. Buyer assumes all responsibility for safe handling and lawful use.

Description

Specifications

  • Form: White lyophilized powder
  • Standard vial size: 1mg
  • Purity: ≥99% (HPLC & Mass Spec verified)
  • Class: 344-amino-acid isoform of the myostatin-binding protein follistatin
  • Storage: Store lyophilized powder at -20°C; refrigerate at 2–8°C once reconstituted

Overview

Follistatin-344 is the longer, heparin-binding isoform of follistatin, a naturally occurring glycoprotein that directly binds and neutralizes myostatin, one of the most potent negative regulators of skeletal-muscle growth.

Mechanism & Research Findings

FST-344 binds myostatin (and related TGF-beta superfamily members like activin) with high affinity, preventing ligand-receptor engagement and thereby blocking the Smad2/3-mediated growth-inhibitory signal. Because it acts through direct ligand sequestration rather than receptor blockade (contrasting with ACE-031’s decoy-receptor mechanism), it is frequently studied comparatively to characterize differences between ligand-trap and receptor-trap approaches to myostatin-pathway inhibition.

Research Applications

  • Myostatin ligand-sequestration research
  • Comparative ligand-trap vs. receptor-trap pathway studies
  • Skeletal-muscle growth-regulation research

For laboratory research use only. Not for human consumption, diagnostic, or therapeutic use.

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