Humanin 10mg

Identity & specification

Amount in vial

Contents

humanin-10mg

Purity

>99%

SKU

humanin-10mg

5 or more 5%
10 or more 10%
50 or more 20%
100 or more 25%

$100.14

Purity

≥99%

Storage

Refrigerate 2–8°C

COA

With every order

Use

Research only

For research use only. Not for human or veterinary use, diagnostic procedures, or food applications. Buyer assumes all responsibility for safe handling and lawful use.

Description

Specifications

  • Form: White lyophilized powder
  • Standard vial size: 10mg
  • Purity: ≥99% (HPLC & Mass Spec verified)
  • Sequence: 24-amino-acid mitochondrial-derived peptide, encoded within the mitochondrial 16S rRNA gene
  • Storage: Store lyophilized powder at -20°C; refrigerate at 2–8°C once reconstituted

Overview

Humanin was the first mitochondrial-derived peptide discovered and remains the most extensively studied member of this peptide class, originally identified in a screen for factors protecting neurons from Alzheimer’s-disease-related toxicity.

Mechanism & Research Findings

Humanin is studied for cytoprotective signaling through multiple pathways, including binding to the CHRNA7/WSX-1/gp130 receptor complex to activate STAT3 signaling, as well as direct interaction with pro-apoptotic Bax protein to inhibit mitochondrial-mediated apoptosis. Research has examined its neuroprotective activity in models of neurodegeneration, along with broader roles in cellular-stress resistance, positioning it as the foundational reference compound in mitochondrial-derived-peptide and cytoprotection research.

Research Applications

  • STAT3 signaling and cytoprotection research
  • Apoptosis (Bax pathway) inhibition studies
  • Neurodegeneration and neuroprotection modeling

For laboratory research use only. Not for human consumption, diagnostic, or therapeutic use.

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