Description

Specifications

• Form: White lyophilized powder
• Standard vial size: 10mg
• Purity: ≥99% (HPLC & Mass Spec verified)
• Sequence: His-D-2-methyl-Trp-Ala-Trp-D-Phe-Lys-NH2
• Storage: Store lyophilized powder at -20°C; refrigerate at 2–8°C once reconstituted, use within 30 days
• CAS Number: 140703-51-1

Overview

Hexarelin is one of the most potent synthetic GHRPs identified to date, notable in the research literature for both its powerful GH-releasing activity and for cardioprotective signaling observed in preclinical cardiac tissue models.

Mechanism & Research Findings

Hexarelin is a strong GHS-R1a agonist that produces a marked GH pulse in animal models, generally regarded as more potent on a molar basis than GHRP-2 or GHRP-6. A distinguishing feature in the literature is Hexarelin’s interaction with a separate, non-GHS-R1a cardiac binding site (CD36), which researchers have linked to direct cardioprotective and anti-fibrotic signaling independent of GH release — making it a compound of interest in cardiac and mitochondrial research models as well as endocrine studies. Its GH-releasing potency also comes with more pronounced desensitization on repeated dosing in animal studies compared to milder secretagogues.

Research Applications

• High-potency GHS-R1a activation studies
• Cardiac tissue / CD36 receptor signaling research
• Comparative GH secretagogue desensitization studies

For laboratory research use only. Not for human consumption, diagnostic, or therapeutic use.