CJC 1295 with DAC

Identity & specification

Amount in vial

Contents

cjc-1295-with-dac

Purity

>99%

SKU

cjc-1295-with-dac

5 or more 5%
10 or more 10%
50 or more 20%
100 or more 25%

£19.99 £44.99Price range: £19.99 through £44.99

Purity

≥99%

Storage

Refrigerate 2–8°C

COA

With every order

Use

Research only

For research use only. Not for human or veterinary use, diagnostic procedures, or food applications. Buyer assumes all responsibility for safe handling and lawful use.

Description

Specifications

  • Form: White lyophilized powder
  • Standard vial size: 2mg / 5mg
  • Purity: ≥99% (HPLC & Mass Spec verified)
  • Sequence: Modified GRF(1-29) conjugated to Drug Affinity Complex (maleimide-based albumin binder)
  • Storage: Store lyophilized powder at -20°C; refrigerate at 2–8°C once reconstituted
  • CAS Number: 863288-34-0 (parent), DAC-conjugated derivative

Overview

CJC-1295 with DAC is the extended-duration version of the same modified GHRH(1-29) fragment, chemically conjugated to a Drug Affinity Complex that binds circulating albumin. This binding dramatically extends its research half-life compared to the non-DAC variant.

Mechanism & Research Findings

By reversibly binding serum albumin, the DAC-conjugated form is protected from rapid proteolytic clearance, producing sustained elevation of GHRH receptor engagement over an extended period in animal pharmacokinetic studies — a sharp contrast to the pulsatile profile of GHRH(1-29) or CJC-1295 without DAC. Researchers use this property specifically to study the physiological consequences of continuous versus pulsatile GHRH receptor stimulation, including downstream effects on IGF-1 production and negative feedback on the GH axis.

Research Applications

  • Sustained-release GHRH receptor occupancy studies
  • Pharmacokinetic / albumin-binding drug delivery research
  • IGF-1 axis feedback modeling

For laboratory research use only. Not for human consumption, diagnostic, or therapeutic use.

Additional information

Dosage

10mg, 2mg, 5mg

CJC 1295 with DAC 2mg

CJC 1295 with DAC 2mgDownload Certificate of Analysis

CJC 1295 with DAC 5mg

CJC 1295 with DAC 5mgDownload Certificate of Analysis

CJC 1295 with DAC 10mg

CJC 1295 with DAC 10mgDownload Certificate of Analysis

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