Description
Specifications
- Form: White lyophilized powder
- Standard vial size: 5mg
- Purity: ≥99% (HPLC & Mass Spec verified)
- Class: Long-acting amylin receptor agonist
- Storage: Store lyophilized powder at -20°C; refrigerate at 2–8°C once reconstituted, use within 30 days
Overview
Cagrilintide is a long-acting synthetic analog of amylin, a pancreatic hormone co-secreted with insulin that plays a role in satiety and gastric emptying. It is often studied alongside GLP-1 agonists for its complementary mechanism of appetite regulation.
Mechanism & Research Findings
Cagrilintide activates amylin (calcitonin) receptors in the area postrema and hypothalamus, slowing gastric emptying and promoting satiety through a pathway distinct from GLP-1 receptor signaling. Because amylin and GLP-1 pathways are non-overlapping, researchers frequently study co-formulated or co-administered Cagrilintide/Semaglutide protocols to characterize additive effects on food intake and body-weight endpoints in animal models — an area of significant current pharmaceutical research interest.
Research Applications
- Amylin receptor pharmacology
- Satiety and gastric-emptying research
- Combination-agonist (amylin + GLP-1) synergy studies
For laboratory research use only. Not for human consumption, diagnostic, or therapeutic use.



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