Ace 031 1mg

Identity & specification

Amount in vial

Contents

ace-031-1mg

Purity

>99%

SKU

ace-031-1mg

5 or more 5%
10 or more 10%
50 or more 20%
100 or more 25%

$60.08

Purity

≥99%

Storage

Refrigerate 2–8°C

COA

With every order

Use

Research only

For research use only. Not for human or veterinary use, diagnostic procedures, or food applications. Buyer assumes all responsibility for safe handling and lawful use.

Description

Specifications

  • Form: White lyophilized powder
  • Standard vial size: 1mg
  • Purity: ≥99% (HPLC & Mass Spec verified)
  • Class: Soluble ActRIIB (Activin Receptor Type IIB) fusion protein
  • Storage: Store lyophilized powder at -20°C; refrigerate at 2–8°C once reconstituted

Overview

ACE-031 is an engineered soluble form of the activin receptor type IIB, developed as a decoy receptor to sequester myostatin and other negative regulators of muscle growth before they can bind their native membrane receptor.

Mechanism & Research Findings

By acting as a high-affinity “trap” for myostatin, GDF-11, and activin A, ACE-031 prevents these ligands from binding native ActRIIB receptors on muscle tissue, blocking the downstream Smad2/3 signaling cascade that normally restrains muscle growth. This mechanism has made it a key reference compound in myostatin-pathway research, particularly in models of muscle-wasting disease where restoring muscle mass via myostatin blockade is the primary research question.

Research Applications

  • Myostatin/activin (Smad2/3) signaling-pathway research
  • Muscle-wasting disease modeling
  • Decoy-receptor / ligand-trap pharmacology research

For laboratory research use only. Not for human consumption, diagnostic, or therapeutic use.

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