Description
Specifications
- Form: White lyophilized powder / crystalline solid
- Standard vial size: 10mg
- Purity: ≥99% (HPLC & Mass Spec verified)
- Class: Small-molecule NNMT inhibitor (not a peptide)
- Storage: Store at -20°C, protect from light and moisture
Overview
5-Amino-1MQ is a small-molecule research compound (distinct from the peptides in this catalog) that selectively inhibits the enzyme nicotinamide N-methyltransferase (NNMT), an emerging target in metabolic and epigenetic research.
Mechanism & Research Findings
NNMT regulates cellular NAD+ and SAM (S-adenosylmethionine) availability by methylating nicotinamide. In adipocyte research models, elevated NNMT activity has been associated with reduced cellular energy expenditure and increased fat storage. By inhibiting NNMT, 5-Amino-1MQ has been studied for its ability to increase intracellular NAD+ and SAM levels, which downstream models suggest can influence adipocyte differentiation and metabolic rate — an active area of epigenetic and obesity-pathway research.
Research Applications
- NNMT enzyme inhibition studies
- NAD+/SAM cellular metabolism research
- Adipocyte differentiation and epigenetic regulation models
For laboratory research use only. Not for human consumption, diagnostic, or therapeutic use.




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