Description
Specifications
- Form: White lyophilized powder
- Standard vial size: 5mg
- Purity: ≥99% (HPLC & Mass Spec verified)
- Sequence: Heptapeptide, Met-Glu-His-Phe-Pro-Gly-Pro (ACTH(4-10) analog)
- Storage: Store lyophilized powder at -20°C; refrigerate at 2–8°C once reconstituted
- CAS Number: 80714-61-0
Overview
Semax is a synthetic heptapeptide derived from ACTH(4-10), developed and studied extensively in Russian neuropharmacology research for its nootropic and neuroprotective properties, independent of ACTH’s hormonal effects.
Mechanism & Research Findings
Semax is studied for its ability to increase brain-derived neurotrophic factor (BDNF) expression and modulate dopaminergic and serotonergic signaling in animal models, without meaningfully affecting the hypothalamic-pituitary-adrenal axis despite its ACTH-fragment origin. Research has examined its effects on memory consolidation, attention, and neuroprotection following ischemic injury in rodent stroke models, making it a frequently referenced compound in BDNF-pathway and cognitive-performance literature.
Research Applications
- BDNF expression and neurotrophic signaling research
- Memory consolidation and attention rodent models
- Ischemic/stroke neuroprotection studies
For laboratory research use only. Not for human consumption, diagnostic, or therapeutic use.



Reviews
There are no reviews yet.