Description
Specifications
- Form: White lyophilized powder
- Standard vial size: 10mg
- Purity: ≥99% (HPLC & Mass Spec verified)
- Sequence: Linear tridecapeptide analog of alpha-MSH
- Storage: Store lyophilized powder at -20°C; refrigerate at 2–8°C once reconstituted
- CAS Number: 75921-69-6
Overview
MT-1 is a synthetic analog of alpha-melanocyte-stimulating hormone, engineered for greater metabolic stability than the native hormone while retaining selective melanocortin-1 receptor (MC1R) activity.
Mechanism & Research Findings
MT-1 selectively activates MC1R on melanocytes, stimulating melanogenesis (eumelanin production) through the cAMP/PKA/CREB signaling pathway. Because of its relative receptor selectivity compared to MT-2, MT-1 is frequently used in pigmentation research as a tool for isolating MC1R-specific effects from the broader multi-receptor activity seen with less selective melanocortin agonists.
Research Applications
- MC1R-selective receptor pharmacology
- Melanogenesis and eumelanin-synthesis research
- Comparative melanocortin-receptor selectivity studies
For laboratory research use only. Not for human consumption, diagnostic, or therapeutic use.


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