MGF 2mg

Identity & specification

Amount in vial

Contents

mgf-2mg

Purity

>99%

SKU

mgf-2mg

5 or more 5%
10 or more 10%
50 or more 20%
100 or more 25%

€17.55

Purity

≥99%

Storage

Refrigerate 2–8°C

COA

With every order

Use

Research only

For research use only. Not for human or veterinary use, diagnostic procedures, or food applications. Buyer assumes all responsibility for safe handling and lawful use.

Description

Specifications

  • Form: White lyophilized powder
  • Standard vial size: 2mg
  • Purity: ≥99% (HPLC & Mass Spec verified)
  • Class: Splice variant of IGF-1 (IGF-1Ec)
  • Storage: Store lyophilized powder at -20°C; refrigerate at 2–8°C once reconstituted, use promptly due to short stability window

Overview

MGF is a splice variant of the IGF-1 gene, distinct from the systemic liver-derived IGF-1Ea isoform, and is expressed locally in skeletal muscle specifically in response to mechanical stress or damage.

Mechanism & Research Findings

Because MGF is expressed locally at the site of muscle microtrauma rather than circulating systemically like hepatic IGF-1, it is studied as a first-responder signal that activates and expands the local satellite (muscle stem) cell pool before the systemic IGF-1Ea isoform drives subsequent protein-synthesis and hypertrophy phases. This distinct temporal and spatial role has made MGF a key compound in research examining the sequential, multi-isoform nature of the IGF-1 gene’s response to mechanical loading.

Research Applications

  • Satellite (muscle stem) cell pool expansion research
  • Local vs. systemic IGF-1 isoform signaling studies
  • Mechanical-loading / exercise-induced gene-splicing research

For laboratory research use only. Not for human consumption, diagnostic, or therapeutic use.

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