Description
Specifications
- Form: White lyophilized powder
- Standard vial size: 5mg
- Purity: ≥99% (HPLC & Mass Spec verified)
- Sequence: 16-amino-acid C-terminal fragment of human growth hormone
- Storage: Store lyophilized powder at -20°C; refrigerate at 2–8°C once reconstituted
- CAS Number: 66004-57-7
Overview
HGH Fragment 176-191 is the unmodified C-terminal fragment of human growth hormone corresponding to its lipolytic domain — the parent structure from which the stabilized analog AOD9604 was later developed.
Mechanism & Research Findings
This fragment retains the lipolytic (fat-metabolizing) signaling of the full GH molecule’s C-terminal region while excluding the N-terminal domains responsible for IGF-1-mediated growth and blood-glucose effects. It is studied as the original reference compound for isolating GH’s fat-metabolism activity from its growth-promoting activity, and is frequently used in comparative pharmacokinetic research against its more stable analog, AOD9604.
Research Applications
- Isolated GH lipolytic-domain research
- Comparative pharmacokinetics vs. AOD9604
- Adipocyte metabolism studies
For laboratory research use only. Not for human consumption, diagnostic, or therapeutic use.







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