Aicar

Identity & specification

Amount in vial

Contents

aicar

Purity

>99%

SKU

aicar

5 or more 5%
10 or more 10%
50 or more 20%
100 or more 25%

$46.72 $73.43Price range: $46.72 through $73.43

Purity

≥99%

Storage

Refrigerate 2–8°C

COA

With every order

Use

Research only

For research use only. Not for human or veterinary use, diagnostic procedures, or food applications. Buyer assumes all responsibility for safe handling and lawful use.

Description

Specifications

  • Form: White lyophilized powder
  • Standard vial size: 50mg
  • Purity: ≥99% (HPLC & Mass Spec verified)
  • Class: Nucleotide analog, AMPK activator
  • Storage: Store lyophilized powder at -20°C, protect from light; refrigerate at 2–8°C once reconstituted
  • CAS Number: 2627-69-2

Overview

AICAR is a cell-permeable nucleoside analog and one of the most widely used tool compounds in AMPK-pathway research, valued for its ability to pharmacologically activate this key metabolic switch independent of upstream signaling.

Mechanism & Research Findings

AICAR is taken up by cells and converted to ZMP, an AMP-mimetic that directly activates AMPK, the master regulator of cellular energy homeostasis. Once activated, AMPK signaling shifts cellular metabolism toward catabolic, energy-generating pathways (fatty-acid oxidation, glucose uptake) while suppressing energy-consuming anabolic processes. AICAR is a foundational reference compound across metabolic-disease, exercise-mimetic, and skeletal-muscle fiber-type research literature.

Research Applications

  • AMPK pathway activation research
  • Exercise-mimetic and skeletal-muscle metabolism studies
  • Glucose-uptake and fatty-acid-oxidation research

For laboratory research use only. Not for human consumption, diagnostic, or therapeutic use.

Additional information

Dosage

100mg, 50mg

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