Description
Specifications
- Form: White lyophilized powder
- Standard vial size: 10mg
- Purity: ≥99% (HPLC & Mass Spec verified)
- Sequence: Octapeptide, acetyl derivative of SNAP-25 fragment
- Storage: Store lyophilized powder at -20°C; refrigerate at 2–8°C once reconstituted
- CAS Number: 868844-74-0
Overview
Snap-8 is a synthetic octapeptide engineered to mimic the N-terminal end of SNAP-25, a protein involved in the SNARE complex that mediates neurotransmitter vesicle release at neuromuscular junctions.
Mechanism & Research Findings
Snap-8 is studied for its ability to interfere with SNARE complex assembly, competitively inhibiting the vesicle-docking process required for acetylcholine release at the neuromuscular junction. This mechanism is studied in vitro as a non-toxin alternative research model for muscle-contraction inhibition pathways, distinct from botulinum-toxin-based approaches, and is frequently referenced in dermal and cosmetic-science research literature examining expression-line formation.
Research Applications
- SNARE complex assembly and neurotransmitter-release research
- Neuromuscular junction pharmacology
- Comparative studies vs. botulinum-toxin mechanism research
For laboratory research use only. Not for human consumption, diagnostic, or therapeutic use.


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